Author

Steven R. Alves

Cold Spring Harbor LaboratoryORCID 0000-0001-9576-6444Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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2026-2026 · peak 2/yr

9 top collaborators · 21 mutual co-author links

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2 shared papersMolecular Biology

Nicholas K. TonksORCID

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2 papers

Molecular BiologyJournal of Biological ChemistryPeer-reviewedMay 20, 2026

This study shows that Ganaxolone inhibits PTP1B, restores TRKB/BDNF signaling, and rescues cellular morphology in CDKL5-deficient cells.

1 citation

Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedFeb 2, 2026

This study shows that inhibiting PTP1B enhances microglial phagocytosis and reduces Aβ burden in AD models by boosting SYK signaling.

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