Jonathan Lalsiamthara

This study shows that NMR-2, an NMDA receptor subunit in C. elegans, regulates pathogen-induced immune responses through neural circuits involving PMK-1, DAF-16, and HLH-30 pathways.

The paper identifies a sensorimotor circuit in C. elegans that mediates learned reflexive aversion to pathogenic bacteria and odors using whole-brain simulation and functional assays.

This study identifies TRPM channels as mediators of learned pathogen avoidance in C. elegans following intestinal distention caused by bacterial colonization.