Adam R. Filipowicz

This study shows that newer insecticides like flupyradifurone cause dopaminergic neurodegeneration in C. elegans, marked by dendritic blebbing and oxidative stress, which can be mitigated by antioxidants or genetic interventions.

The paper identifies a sensorimotor circuit in C. elegans that mediates learned reflexive aversion to pathogenic bacteria and odors using whole-brain simulation and functional assays.

This study identifies TRPM channels as mediators of learned pathogen avoidance in C. elegans following intestinal distention caused by bacterial colonization.