Author

Alejandro Aballay

Oregon Health & Science UniversityORCID 0000-0002-5975-3352Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Genetics· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:C. elegans· 4 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Jonathan LalsiamtharaiD· 3 shared Adam R. FilipowicziD· 2 shared Ernesto Satoshi NakayasuiD· 2 shared Aaron J. OgdeniD· 1 shared Benson OtarighoiD· 1 shared Cameron G. RobertsiD· 1 shared Donghoon KangiD· 1 shared Gus D. WarreniD· 1 shared

Activity by Year

2021-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersNeuroscience

Jonathan LalsiamtharaORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A functional screen for ubiquitin regulation identifies an E3 ligase secreted by Pseudomonas aeruginosa

Cameron G. Roberts, Supender Kaur, Shun‐Je Bhark, Aaron J. Ogden, Michael E. Divine, Gus D. Warren, Donghoon Kang, Natalia V. Kirienko, Paul P. Geurink, Monique P. C. Mulder, Ernesto Satoshi Nakayasu, Jason McDermott, Joshua Adkins, Alejandro Aballay, Jonathan N. Pruneda

This study identifies a novel E3 ligase secreted by Pseudomonas aeruginosa that regulates virulence through ubiquitin modification.

The EMBO Journal · Sep 28, 2026Peer-reviewedMicrobiology

NMDA Receptor Subunit NMR-2 Regulates Pathogen-Induced Immune Responses via the Nervous System in C. elegans

Benson Otarigho, Jonathan Lalsiamthara, Alejandro Aballay

This study shows that NMR-2, an NMDA receptor subunit in C. elegans, regulates pathogen-induced immune responses through neural circuits involving PMK-1, DAF-16, and HLH-30 pathways.

Communications Biology · Aug 11, 2026Peer-reviewedImmunology

Intestinal lipid metabolism controls immune response through NHR-68 and gut-brain signaling in C. elegans

Jie Ren, Yu Sang, Young‐Mo Kim, Ernesto Satoshi Nakayasu, Alejandro Aballay

This study shows that NHR-68 in C. elegans links intestinal lipid metabolism to immune and behavioral responses through gut-brain signaling.

bioRxiv · Jun 29, 2026 · PreprintGenetics

Dissection of a sensorimotor circuit that regulates aversion to odors and pathogenic bacteria in C. elegans by whole-brain simulation

Adam R. Filipowicz, Jonathan Lalsiamthara, Alejandro Aballay

The paper identifies a sensorimotor circuit in C. elegans that mediates learned reflexive aversion to pathogenic bacteria and odors using whole-brain simulation and functional assays.

bioRxiv · Apr 21, 2022 · PreprintNeuroscience

TRPM channels mediate learned pathogen avoidance following intestinal distention

Adam R. Filipowicz, Jonathan Lalsiamthara, Alejandro Aballay

This study identifies TRPM channels as mediators of learned pathogen avoidance in C. elegans following intestinal distention caused by bacterial colonization.

eLife · May 25, 2021Peer-reviewedNeuroscience