Kevan P. Clifford

This study links the FREM3 gene to brain and cognitive aging using cross-species evidence from mice and humans, showing reduced brain volume and cognitive performance in Frem3 knockout mice and lower FREM3-GReX associated with reduced brain surface area and cognitive performance in humans.

This study investigates how acute and chronic stress affect neuronal and astroglial activity and communication in the prefrontal cortex, finding that chronic stress impairs neuron-astroglia coupling and is linked to behavioral deficits.

The paper develops sex-specific transcriptome-based polygenic risk scores for depression and evaluates their associations with brain structure and symptoms in adolescents.

The paper develops polygenic risk scores for molecular brain aging and links them to cortical thickness and cognitive performance in older adults.

This study examines age-related changes in brain structure and cognition in mice, finding volume and network differences associated with maturation and aging.