Yuliya S. Nikolova

This study links the FREM3 gene to brain and cognitive aging using cross-species evidence from mice and humans, showing reduced brain volume and cognitive performance in Frem3 knockout mice and lower FREM3-GReX associated with reduced brain surface area and cognitive performance in humans.

This study investigates how acute and chronic stress affect neuronal and astroglial activity and communication in the prefrontal cortex, finding that chronic stress impairs neuron-astroglia coupling and is linked to behavioral deficits.

The paper develops sex-specific transcriptome-based polygenic risk scores for depression and evaluates their associations with brain structure and symptoms in adolescents.

The paper develops polygenic risk scores for molecular brain aging and links them to cortical thickness and cognitive performance in older adults.

This study examines age-related changes in brain structure and cognition in mice, finding volume and network differences associated with maturation and aging.

This paper develops a transcriptome-based polygenic risk score (T-PRS) linking depression-related cortical gene expression changes to brain morphology and symptom severity in MDD.

This study shows chronic amygdala hyperactivation in mice increases anxiety and may worsen stress-induced anxiety but does not cause depressive-like behaviors.

The paper investigates genetic overlap between major depression, bipolar disorder, and Alzheimer's disease using GWAS data and identifies shared genetic correlations and pleiotropic genes.

The paper develops a transcriptome-based polygenic risk score (T-PRS) linking depression-related gene expression changes to neural face processing and anhedonia in a non-clinical sample.

The paper identifies structural neuroimaging signatures of anorexia nervosa symptoms and risk factors in a sample enriched for disease vulnerability using MRI and DTI data.