Lucía Conde

The paper reanalyzes CLAP data to show PRC2 directly interacts with RNA in cells, correcting previous findings that missed this interaction due to a scaling step.

This study shows that a specific PTEN mutation causes macrocephaly, lymphoid overgrowth, and late-onset cancer in mice by impairing nuclear PTEN functions, while maintaining normal PI3K/AKT signaling.

The paper tracks the epigenetic fate of endogenous retroviruses during neural differentiation, identifying genetic escapees that evade TRIM28 repression and contribute to gene expression differences.

GenomeChronicler generates genomic reports from whole genome or exome sequencing data, linking variants to known phenotypes using public databases.

The paper describes the PGP-UK multi-omics reference panel, providing open access to genomic, methylomic, and transcriptomic data with quality control and API access.

PGP-UK explores citizen science in genomics by recruiting participants, sharing data, and developing tools to advance personalized medicine.