Peter Hortschansky

This study identifies SmpR as a transcription factor that coordinates secondary metabolism and antibacterial defense in A. fumigatus in response to bacterial signals.

The paper identifies a single amino acid change in fungal proteins that enables phagosomal membrane penetration, suggesting convergent evolution of virulence mechanisms across fungi.

The paper investigates the regulatory motifs in the cyp51A promoter of Aspergillus fumigatus that contribute to azole resistance, revealing iron-dependent and -independent roles of transcription factors.