Author

Kathryn L. Schwertfeger

University of MinnesotaORCID 0000-0002-9755-7774Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

David K. WoodiD· 2 shared Alexandra L. CramptoniD· 1 shared Alisa B. NelsoniD· 1 shared Andrew E. GoodspeediD· 1 shared Andy NelsoniD· 1 shared Arthur T. JohnsoniD· 1 shared Braedan M. McCluskeyiD· 1 shared Camryn S. NesibaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

David K. WoodORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CDH1 loss remodels gene expression and lineage identity in human mammary epithelial cells

Maggie Musick, Chinasa A Ufondu, Carmen E. Rowland, Micaela E. Brown, Joseph L. Sottnik, Madeleine T. Shackleford, Camryn S. Nesiba, Etienne P. Danis, Andrew E. Goodspeed, Richard Zera, Arthur T. Johnson, Kathryn L. Schwertfeger, Andy Nelson, Julie Hanson Ostrander, Matthew J. Sikora

This study shows that CDH1 loss in human mammary epithelial cells remodels gene expression and lineage identity toward a luminal progenitor-like state, contributing to ILC oncogenesis.

PLoS Genetics · Oct 27, 2026Peer-reviewedCancer Biology

Collagen-Based Tumor Spheroid Model for Investigating Tumor-Macrophage Interactions through Extracellular Matrix Remodeling

Luna Zhang, Sanab Abdi, Hannah M. Szafraniec, Paolo P. Provenzano, Kathryn L. Schwertfeger, David K. Wood

This paper develops a 3D collagen-based tumor spheroid model to study macrophage-driven ECM remodeling and its impact on cancer cell invasion and malignancy.

bioRxiv · Oct 1, 2025 · PreprintCancer Biology

Deciphering Colorectal Cancer-Hepatocyte Interactions: A Multiomic Platform for Interrogation of Metabolic Crosstalk in the Liver-Tumor Microenvironment

Alisa B. Nelson, Lyndsay E. Reese, Elizabeth Rono, Eric D. Queathem, Yinjie Qiu, Braedan M. McCluskey, Alexandra L. Crampton, Eric Conniff, Katherine A. Cummins, Ella Boytim, Senali Dansou, Justin H. Hwang, Sandra E. Safo, Patrycja Puchalska, David K. Wood, , Peter A. Crawford

This study uses multiomic analysis to investigate metabolic interactions between colorectal cancer cells and hepatocytes in liver metastasis, revealing metabolic shifts and potential therapeutic targets.

International Journal of Molecular Sciences · Feb 25, 2025Peer-reviewedBioinformatics