Molecular BiologyNucleic Acids ResearchPeer-reviewed
OCT4 activates a Suv39h1-repressive antisense lncRNA to couple histone H3 Lysine 9 methylation to pluripotency
Laure D. Bernard, Agnès Dubois, Victor Heurtier…·Pablo Navarro
The paper identifies a genetic circuitry where OCT4 activates an antisense lncRNA that represses Suv39h1, linking H3K9 methylation levels to pluripotency in mouse ES cells.
16 citations