The GLP-1 analogue, exendin-4, improves bone material properties and strength through a central relay in ovariectomized mice
Morgane Mermet, Jessica Denom, Aleksandra Mieczkowska, Méline Wery, Emma K. Biggs, Fiona Mary Gribble, Frank M. Reimann, Chr̀istophe Magnan, Céline Cruciani‐Guglielmacci, Guillaume Mabilleau
This study shows that exendin-4 improves bone strength in ovariectomized mice through a central mechanism, not directly on bone cells.
American Journal of Physiology-Endocrinology and Metabolism · Aug 12, 2025Peer-reviewedPhysiology