Author

Emma K. Biggs

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Fiona Mary GribbleiD· 2 shared Frank M. ReimanniD· 2 shared Adam S. ButterworthiD· 1 shared Albert KoulmaniD· 1 shared Aleksandra MieczkowskaiD· 1 shared Angela WoodiD· 1 shared Céline Cruciani‐GuglielmacciiD· 1 shared Chen LiiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPhysiology

Fiona Mary GribbleORCID

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2 papers

Recent·Most cited

The GLP-1 analogue, exendin-4, improves bone material properties and strength through a central relay in ovariectomized mice

Morgane Mermet, Jessica Denom, Aleksandra Mieczkowska, Méline Wery, Emma K. Biggs, Fiona Mary Gribble, Frank M. Reimann, Chr̀istophe Magnan, Céline Cruciani‐Guglielmacci, Guillaume Mabilleau

This study shows that exendin-4 improves bone strength in ovariectomized mice through a central mechanism, not directly on bone cells.

American Journal of Physiology-Endocrinology and Metabolism · Aug 12, 2025Peer-reviewedPhysiology

Cross-platform genetic discovery of small molecule products of metabolism and application to clinical outcomes

Luca Andrea Lotta, Maik Pietzner, Isobel D. Stewart, Laura B. L. Wittemans, Chen Li, Roberto Bonelli, Johannes Raffler, Emma K. Biggs, Clare Oliver‐Williams, Victoria P.W. Auyeung, Jian’an Luan, Eleanor Wheeler, Ellie Paige, Praveen Surendran, Gregory Alexander Michelotti, , Claudia Langenberg

This study identifies genetic associations with metabolite levels across multiple cohorts and links these variants to clinical outcomes like type 2 diabetes and macular telangiectasia type 2.

bioRxiv · Feb 3, 2020 · PreprintGenetics