Tsuyoshi Inoue A

The paper identifies RvPeti, a novel metalloprotease from a tardigrade, through structural and biochemical analysis, revealing its Zn2+-dependent proteolytic activity.

This study uses purification-free cryo-EM to analyze endogenous macromolecular assemblies from tardigrade samples, revealing structures like vitellogenin and ferritin.

This study characterizes the structure and function of RvPrxL, a neofunctionalized peroxiredoxin from tardigrades that binds nucleic acids in the nucleus.

The paper reports the cryo-EM structure of CYP2C9, revealing a dimer-of-trimers assembly and its stabilization mechanisms.

This study identifies a copper-dependent redox receptor in plants that perceives hydrogen peroxide through a surface-bound copper ion.

The paper presents the high-resolution structure of a microtubule-like tube formed by FtsZ-monobody complexes, revealing structural similarities to microtubules and the role of FtsZ protofilament plasticity.

The paper introduces an epoxidized graphene grid (EG-grid) that improves particle density and orientation in cryoEM, enabling high-resolution structural analysis with fewer micrographs.

The paper presents nine alpaca nanobodies that recognize conserved hidden epitopes on SARS-CoV-2 spike proteins across variants and maintain neutralizing activity against escape mutations.