Cerebral Organoids with Integrated Endothelial Networks Emulate the Neurovascular Unit and Mitigate Core Necrosis
Josep Fumadó Navarro, Siobhan Crilly, Wai Kit Chan, S. Browne, John O. Mason, Catalina Vallejo‐Giraldo, Abhay S. Pandit, Mihai Lomora
Embedding day-8 cerebral organoids in Geltrex loaded with human brain microvascular endothelial cells, plus VEGF-supplemented mixed media, yields integrated endothelial networks and almost three-fold less apoptosis.
Advanced Science · Aug 30, 2025Peer-reviewedBioengineering✦ In-depth digest