Erika Vitiello

The paper identifies late endosomes as selective RNA carriers in motor neurons and shows that ALS-linked FUS mutations disrupt this process.

This study identifies LINC00205 as a critical lncRNA that promotes the formation of pathological stress granules in ALS by acting as a scaffold to recruit specific mRNAs and proteins.

The paper develops a near-infrared aptamer:dye system for live-cell super-resolution RNA imaging through evolutionary approaches and chemical optimization.

The paper uses Pepper fluorescent RNA to visualize and study the dynamics of circRNAs and lncRNAs in live cells, revealing their interactions with pathological aggregates and stress granules.

This study examines how ALS-associated FUS mutations alter the RNA and protein composition of Stress Granules in neural cells, revealing molecular changes linked to neurodegeneration.