Author

Chen Liu

Yale UniversityORCID 0000-0001-5416-8464Unclaimed ORCID profile · follow to get notified of new preprints

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Chen Liu6 papers · Yale University

Biology Disciplines

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Genetics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:long-read sequencing· 1 Assay:protein sequence· 1

Frequent Co-Authors

Smita KrishnaswamyiD· 2 shared Akiko IwasakiiD· 1 shared Alexis WeinrebiD· 1 shared Arman AfrasiyabiiD· 1 shared David M. MilleriD· 1 shared Edward Yang· 1 shared Egbert CastroiD· 1 shared Erdem VaroliD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

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10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Smita KrishnaswamyORCID

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2 papers

Recent·Most cited

ImmunologyNature Machine IntelligencePeer-reviewedDec 31, 2025

ImmunoStruct: a multimodal neural network framework for immunogenicity prediction from peptide-MHC sequence, structure, and biochemical properties

Kevin Bijan Givechian, João Felipe Rocha, Chen Liu…·Smita Krishnaswamy

ImmunoStruct improves immunogenicity prediction by integrating peptide-MHC sequence, structure, and biochemical data, showing better performance than existing methods.

7 citations

protein sequenceprotein structure

𝕏 PostBluesky

GeneticsbioRxivPreprintJun 22, 2025

CellSpliceNet: Interpretable Multimodal Modeling ofAlternative Splicing Across Neurons in C. elegans

Arman Afrasiyabi, Jake Kovalic, Chen Liu…·Smita Krishnaswamy

CellSpliceNet predicts alternative splicing outcomes in C. elegans neurons by integrating multiple data modalities and achieving high predictive accuracy.

DOI 10.1101/2025.06.22.660966

C. eleganslong-read sequencing

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