Yin Wan

This study identifies key oncogenic pathways and targetable genes in MEN1-wild-type low-grade pancreatic NETs that drive metastasis, offering a therapeutic strategy based on pathway intensity rather than mutation count.

The paper shows that certain bacteria reduce microsporidia infection in C. elegans by altering host metabolism and producing inhibitory compounds.

The paper introduces MCMC-CE, an algorithm for estimating small right-tail probabilities of quadratic forms, showing improved accuracy and efficiency in genomics applications.

This study shows that combining PCNA inhibitor AOH1996 with KRAS inhibitors enhances antitumor activity in pancreatic cancer models.

This study identifies HNF1A as an oncogenic driver of PDAC metastasis through upregulation of FGFR4 and shows that FGFR4 inhibition reduces metastasis in vitro and in vivo.