Stylianos Bournazos

This study identifies hr2.016, a potent and broad SARS-CoV-2 neutralizing antibody, and shows its neutralization depends on kinetic stability and avidity.

The paper identifies two human monoclonal antibodies that neutralize West Nile virus and related orthoflaviruses, offering potential for antibody-based interventions.

This study identifies Fc gamma receptor-dependent and independent mechanisms by which pre-existing antibodies enhance germinal center and plasmablast responses and alter the affinity threshold for B cell recruitment.

This paper elucidates the mechanistic basis for the selective recognition of FcγRIIa by monoclonal antibody IV.3 through a combination of experimental and computational methods.

This study shows that IgG's anti-inflammatory activity depends on the interaction between Fc{gamma}RIIB and DC-SIGN, and engineering sialylated IgG1 enhances its potency in treating autoimmune diseases.

This study identifies non-neutralizing antibodies from vaccinated individuals that protect against SARS-CoV-2 in animal models, highlighting their role through Fc-mediated effector functions and conserved epitope binding.