Nicholas Bertos

The paper identifies a cold fibrotic network in LUSC TME driven by CAFs and shows its conservation in other CIACs, suggesting therapeutic targets.

The paper identifies a fibroblast state called STIF that drives YAP-dependent regenerative programs and (pre)malignancy through mechanotransduction in response to tissue injury.

The paper establishes a large-scale biobank of GEA patient-derived organoids that accurately model tumor features and drug responses, enabling personalized treatment strategies.

CrosstalkNet is a web-based tool for visualizing and analyzing large-scale bipartite co-expression networks to study tumor-stromal cell interactions.