Will Wood

The paper identifies hypoxanthine as a key metabolite released during apoptosis that is consumed by gut bacteria, impairing epithelial repair.

The paper shows that phagosome-induced nuclear deformation in Drosophila macrophages increases Lamin B levels, enhancing phagocytic capacity.

The paper develops fluorogenic chemical probes that detect membrane damage without washing steps, enabling in vivo imaging of cell death mechanisms like ferroptosis and necrosis.