Author

Frank Schwach

Wellcome Sanger InstituteORCID 0000-0001-5495-7535Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:plant (other)· 2 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Ellen BushelliD· 3 shared Gareth GirlingiD· 3 shared Julian C. RayneriD· 3 shared Oliver BillkeriD· 3 shared Theo SandersoniD· 2 shared A. Roberts· 1 shared Allan MuhweziiD· 1 shared Andrew J. C. RusselliD· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersMicrobiology

Ellen BushellORCID

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintSep 5, 2024

Application of barcode sequencing to increase the throughput and complexity of Plasmodium falciparum genetic screening

Allan Muhwezi, Mehdi Ghorbal, Theo Sanderson…·Julian C. Rayner

The paper uses barcoded P. falciparum gene knockouts with BarSeq to phenotype parasite life cycle traits at scale.

2 citations

plant (other)bulk RNA-seq

𝕏 PostBluesky

MicrobiologybioRxivPreprintAug 27, 2024

A novel chemogenomic screening platform for scalable antimalarial drug target identification

Christopher Bower-Lepts, Mukul Rawat, William Collins Keith…·Julian C. Rayner

This paper develops a chemogenomic platform using Plasmodium berghei artificial chromosomes to identify antimalarial drug targets through barcode sequencing and validation in Plasmodium falciparum.

4 citations

plant (other)bulk RNA-seq

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GenomicsCell Host & MicrobePeer-reviewedJan 11, 2023

Regulators of male and female sexual development critical for transmission of a malaria parasite

Andrew J. C. Russell, Theo Sanderson, Ellen Bushell…·Oliver Billker

The paper identifies ten genes critical for male and female sexual development in Plasmodium berghei and reveals a regulatory cascade governing gametogenesis.

72 citationstop 1%

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