Ellen Bushell

This study identifies two Plasmodium virulence factors involved in lipid metabolism and disease progression by analyzing their function in vivo.

The paper develops a scalable CRISPR-Cas9 system for Plasmodium berghei to enable genome-wide knockout screens.

The paper uses barcoded P. falciparum gene knockouts with BarSeq to phenotype parasite life cycle traits at scale.

This paper develops a chemogenomic platform using Plasmodium berghei artificial chromosomes to identify antimalarial drug targets through barcode sequencing and validation in Plasmodium falciparum.

The paper identifies EMAP3 as a new parasite protein exposed on the surface of P. berghei infected red blood cells, which interacts with EMAP1 but is not the main CD36-binding protein.

The paper identifies ten genes critical for male and female sexual development in Plasmodium berghei and reveals a regulatory cascade governing gametogenesis.

The paper reports the genome sequencing of two avian malaria parasites and identifies lineage-specific features associated with their evolution in birds and mammals.