Andrew J. C. Russell

This study uses spatial transcriptomics and lineage tracing to show how tumor subclones drive microenvironmental changes that promote metastasis in a mouse model.

The paper induces menstruation in mice to study endometrial shedding regulation, revealing a new paradigm for spatially regulated fibroblast differentiation.

Slide-tags enables spatial localization of single nuclei for multi-modal spatial genomics, achieving high-resolution mapping and multiomic profiling in various tissues.

The paper identifies ten genes critical for male and female sexual development in Plasmodium berghei and reveals a regulatory cascade governing gametogenesis.

The paper creates a comprehensive single-cell transcriptome atlas of the Plasmodium berghei life cycle and applies it to define stages in human malaria parasites.

This paper shows CRISPRi is not strand-specific and alters transcription by enabling both sense and antisense transcript generation.