Author

Wen Tang

Research Institute of Molecular Pathology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

Click to filter author papers

Genomics· 3 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:Hi-C· 4 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:ChIP-seq· 1 Organism:mouse· 1 Approach:simulation· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Gordana WutziD· 4 shared Jan‐Michael PetersiD· 4 shared Roman R. StocsitsiD· 4 shared Edward J. BaniganiD· 2 shared Johannes A. ZuberiD· 2 shared Kota NagasakaiD· 2 shared Leonid A. MirnyiD· 2 shared Matthias MuhariD· 2 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersGenomics

Gordana WutzORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

PDS5 proteins control genome architecture by limiting the lifetime of cohesin-NIPBL complexes

Gordana Wutz, Iain F. Davidson, Edward J. Banigan, Roman R. Stocsits, Ryotaro Kawasumi, Wen Tang, Kota Nagasaka, Lorenzo Costantino, Ralf Jansen, Kouji Hirota, Dana Branzei, Leonid A. Mirny, Jan‐Michael Peters

This study shows PDS5 proteins regulate genome architecture by stopping loop extrusion and strengthening CTCF boundaries through NIPBL dissociation from cohesin.

Molecular Cell · Apr 23, 2026Peer-reviewedMolecular Biology

Transcription shapes 3D chromatin organization by interacting with loop extrusion

Edward J. Banigan, Wen Tang, Aafke A. van den Berg, Roman R. Stocsits, Gordana Wutz, Hugo B. Brandão, Georg A. Busslinger, Jan‐Michael Peters, Leonid A. Mirny

The paper shows that transcribing RNA polymerases act as moving barriers to cohesin, altering chromatin organization near active genes.

Proceedings of the National Academy of Sciences · Mar 10, 2023Peer-reviewedGenomics

Cohesin-dependent and independent mechanisms support chromosomal contacts between promoters and enhancers

Michiel J. Thiecke, Gordana Wutz, Matthias Muhar, Wen Tang, Stephen Bevan, Valeriya Malysheva, Roman R. Stocsits, Tobias Neumann, Johannes A. Zuber, Peter Fraser, Stefan Schoenfelder, Jan‐Michael Peters, Mikhail Spivakov

The paper investigates chromosomal contacts between promoters and enhancers using Capture Hi-C, showing that cohesin depletion affects long-range contacts but not shorter-range ones.

Cell Reports · Jul 1, 2020Peer-reviewedGenomics

CTCF, WAPL and PDS5 proteins control the formation of TADs and loops by cohesin

Gordana Wutz, Csilla Várnai, Kota Nagasaka, David A. Cisneros, Roman R. Stocsits, Wen Tang, Stefan Schoenfelder, Gregor Jessberger, Matthias Muhar, M. Julius Hossain, Nike Walther, Birgit Koch, Moritz Kueblbeck, Jan Ellenberg, Johannes A. Zuber, , Jan‐Michael Peters

This study demonstrates that CTCF, WAPL, and PDS5 proteins regulate TADs and loops by controlling cohesin's interaction with chromatin.

The EMBO Journal · Dec 7, 2017Peer-reviewedGenomics