Sue E. Knoblaugh

This study shows that a ketogenic diet prevents obesity-associated pancreatic cancer without weight loss but may promote cancer in non-obese models, altering specific metabolic pathways.

This study shows that Stearoyl-CoA Desaturases (SCDs) regulate intestinal stem and progenitor cell metabolism and function in response to nutrient abundance, affecting tissue homeostasis and regeneration.

This study generates mice with reduced NRF1 function in β-cells, showing impaired β-cell function and mitochondrial defects leading to diabetes.