Author

Thiago S. Freire

Universidade de São PauloORCID 0000-0001-5509-3230Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Milena Siolin MartinsiD· 1 shared Nadja Cristhina de Souza-PintoiD· 1 shared Neiliane SimaiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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1 shared paperBiochemistry

Milena Siolin MartinsORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintApr 22, 2025

Ebselen protects XPC deficient cells through a potentially mitohormetic mechanism

Thiago S. Freire, Milena Siolin Martins, Neiliane Sima, Nadja Cristhina de Souza-Pinto

This study shows ebselen protects XPC deficient cells at low doses but harms them at high doses, suggesting a mitohormetic mechanism involving redox stress and mitochondrial adaptation.

DOI 10.1101/2025.04.22.650012

humanexperimental assay

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