BiochemistrybioRxivPreprint
Ebselen protects XPC deficient cells through a potentially mitohormetic mechanism
Thiago S. Freire, Milena Siolin Martins, Neiliane Sima, Nadja Cristhina de Souza-Pinto
This study shows ebselen protects XPC deficient cells at low doses but harms them at high doses, suggesting a mitohormetic mechanism involving redox stress and mitochondrial adaptation.
DOI 10.1101/2025.04.22.650012