Nadja Cristhina de Souza-Pinto

This study identifies PARG activity as essential for parthanatos cell death, showing that both PAR formation and hydrolysis are required, and reveals a new PARG splice variant.

This study identifies XPC as essential for protecting Th17 cells from oxidative DNA damage, showing its role in DNA repair, differentiation, and function.

This study develops an RP-HPLC method with UV-Vis detection to simultaneously quantify multiple adenine nucleotides in mammalian cells, showing sensitivity and applicability in pharmacological studies.

This study shows ebselen protects XPC deficient cells at low doses but harms them at high doses, suggesting a mitohormetic mechanism involving redox stress and mitochondrial adaptation.

The paper shows DNA repair gene expression decreases during olfactory sensory neuron differentiation and is lower in olfactory epithelium compared to non-olfactory brain regions.