Gang Pei

This study reconstructs 3D spatial transcriptomic models of planarians to map cell type distribution and positional gene regulation, identifying candidate genes involved in regeneration.

This paper develops a human gut-BBB-brain microphysiological model to study neurodegenerative diseases and finds that gut-brain interactions can promote brain organoid maturation and recapitulate AD pathology.

This study constructs a 4D spatiotemporal transcriptomic map of planarian regeneration using Stereo-seq, identifying dynamic gradients and an injury-induced regenerative zone.

This study identifies BANF1 as a host factor essential for ASFV replication and reveals that A151R and MGF360-21R inhibit the IFN-I response, independent of BANF1.

This study uses bat epithelial organoids to investigate antiviral immunity differences between bats and humans, revealing unique interferon responses and implications for viral pathogenesis.

The paper develops a secretome profiling method for astrocytes and identifies proteins involved in disease-related toxicity and neuroprotection.