Author

Pankaj Singh Thapa

International Institute of Molecular and Cell BiologyORCID 0000-0001-5536-1768Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Assay:proteomics· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Natalia A. SzulciD· 3 shared Wojciech PokrzywaiD· 3 shared Aniruddha DasiD· 1 shared Anwesha SarkariD· 1 shared Carlos Jaime CamachoiD· 1 shared Dominik CysewskiiD· 1 shared Hendrik NolteiD· 1 shared Katarzyna Banasiak· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMolecular Biology

Natalia A. SzulcORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 16, 2025

A dosage-sensitive ALLO-1 network coordinates mitochondrial quality control to enable functional recovery of structurally compromised muscle

Anwesha Sarkar, Lilla Biriczová, Natalia A. Szulc…·Wojciech Pokrzywa

The paper identifies an ALLO-1 network that coordinates mitochondrial quality control in C. elegans muscle, enabling functional recovery despite structural damage.

DOI 10.1101/2025.10.16.682884

C. elegansproteomics

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Molecular BiologybioRxivPreprintJan 18, 2023

Lysine-deficient proteome can be regulated through non-canonical ubiquitination and ubiquitin-independent proteasomal degradation

Natalia A. Szulc, Małgorzata Piechota, Pankaj Singh Thapa, Wojciech Pokrzywa

The paper identifies lysine deserts in UPS components across species and shows they can be regulated by non-lysine ubiquitination and ubiquitin-independent proteasomal degradation.

3 citations

bacteria (other)human

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Molecular BiologyThe EMBO JournalPeer-reviewedJun 28, 2022

Heterotypic Assembly Mechanism Regulates CHIP E3 Ligase Activity

Aniruddha Das, Pankaj Singh Thapa, Ulises Santiago…·Wojciech Pokrzywa

The paper investigates how the CHN-1/UFD-2 complex enhances ubiquitin chain formation through dimerization and chaperone-mediated regulation of substrate ubiquitylation.

17 citations

C. elegansexperimental assay

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