Author
University of PittsburghORCID 0000-0003-2259-5984Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Guowu Lin, Paola Zinser Peniche, Xiaohong Zhou…·Guillermo A. Calero
This study uses time-resolved crystallography to capture GTP hydrolysis intermediates of N-RAS and oncogenic mutants, revealing shared and distinct reaction mechanisms.
Sandra Viviana Vergara, Xiaohong Zhou, Ulises Santiago…·Guillermo A. Calero
This study captures 11 structures of HIV-1 reverse transcriptase during DNA synthesis, revealing intermediate states and mechanisms of dATP incorporation and drug resistance.
Aniruddha Das, Pankaj Singh Thapa, Ulises Santiago…·Wojciech Pokrzywa
The paper investigates how the CHN-1/UFD-2 complex enhances ubiquitin chain formation through dimerization and chaperone-mediated regulation of substrate ubiquitylation.