Haixin Li

A nuclear role for the Argonaute protein AGO2 in mammalian gametogenesis

This study identifies a nuclear role for AGO2 in spermatogenesis, showing it enhances protein expression by interacting with splicing and chromatin factors.

NEURON-SPECIFIC CHROMOSOMAL MEGADOMAIN ORGANIZATION IS ADAPTIVE TO RECENT RETROTRANSPOSON EXPANSIONS

The paper shows that neuron-specific chromatin domains in mice are shaped by recent retrotransposon expansions and that disrupting a silencer leads to chromatin rewiring and neuroinflammation.

DAZL is a master translational regulator of murine spermatogenesis

This study identifies DAZL as a master translational regulator essential for murine spermatogenesis by showing its role in maintaining spermatogonial stem cells and preventing meiotic arrest.