Author
Brigham and Women's HospitalORCID 0000-0001-5540-9442Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Alexander O. Ward, Nicole Schönrock, Alex J. McCann…·Richard Paul Harvey
The paper investigates NKX2-5 mutations in congenital heart disease by analyzing their epigenomic, biochemical, and chromatin search functions in cardiomyocytes, revealing diverse loss and gain-of-function defects.
Luke Lambourne, Kaia Mattioli, Clarissa Stephanie Santoso…·Juan I. Fuxman Bass
The paper identifies two categories of transcription factor isoforms with distinct molecular functions and shows they contribute to gene regulatory complexity.
Kian Hong Kock, Patrick K. Kimes, Stephen S. Gisselbrecht…·Martha L. Bulyk
The paper analyzes DNA binding effects of 92 human homeodomain mutants, identifying 14 novel specificity-determining residues and highlighting limitations of variant effect prediction tools.