Ziyu Chen

This paper develops a closed-loop cell therapy that secretes an Activin A inhibitor to prevent heterotopic bone formation in a mouse model of FOP.

This study evaluates 11 genomic language models and finds they offer limited advantages over a random baseline in regulatory decoding tasks.

This study identifies rosiglitazone, a PPARγ agonist, as a potential therapy for fibrodysplasia ossificans progressiva and trauma-induced heterotopic ossification by converting ectopic bone to fat.