Author

Samerender Nagam Hanumantharao

Brigham and Women's HospitalORCID 0000-0003-2087-4189Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Ashley Emily SiegeliD· 2 shared David E. MaridasiD· 2 shared Pratik KoiralaiD· 2 shared Shailesh AgarwaliD· 2 shared Vicki RoseniD· 2 shared Yuji M. MishinaiD· 2 shared Ziyu CheniD· 2 shared Chang LiuiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersCell Biology

Ashley Emily SiegelORCID

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2 papers

Recent·Most cited

Cell BiologyiSciencePeer-reviewedJul 1, 2026

A closed-loop cell therapy engineered to autonomously secrete Activin A inhibitor protects from fibrodysplasia ossificans progressiva

Pratik Koirala, Ziyu Chen, Mengfan Wu…·Shailesh Agarwal

This paper develops a closed-loop cell therapy that secretes an Activin A inhibitor to prevent heterotopic bone formation in a mouse model of FOP.

DOI 10.1016/j.isci.2026.116602

mouseexperimental assay

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Cell BiologybioRxivPreprintMar 16, 2026

Activation of PPARγ redirects fibro-adipogenic progenitors to replace ectopic bone with fat in models of fibrodysplasia ossificans progressiva and trauma-induced heterotopic ossification

Pratik Koirala, Ziyu Chen, Samerender Nagam Hanumantharao…·Shailesh Agarwal

This study identifies rosiglitazone, a PPARγ agonist, as a potential therapy for fibrodysplasia ossificans progressiva and trauma-induced heterotopic ossification by converting ectopic bone to fat.

DOI 10.64898/2026.02.26.708276

mousestatistical model

𝕏 PostBluesky