Suzanne Scarlata

The paper evaluates seven GNAI1 disorder variants in C. elegans and human cells to determine their impact on ciliogenesis and neuronal function, identifying conserved and cell-specific mechanisms of dysfunction.

This study shows ESCRT-I and ALIX form helical filaments in vivo, serving as structural scaffolds and ESCRT-III assembly templates for membrane scission and viral budding.

This study shows that repeated Gαq activation in C. elegans leads to stress granule accumulation and age-dependent neuronal defects, reducing lifespan.