Author

Stephanie J. Spada

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

Fadila Bouamr· 2 shared Michael E. GriggiD· 2 shared Sonja M. BestiD· 2 shared Abhilash I. Chiramel· 1 shared Adam HageiD· 1 shared Aleksandra Nita‐LazariD· 1 shared Byron ShueiD· 1 shared Charles L. LarsoniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMicrobiology

Fadila Bouamr

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2 papers

Recent·Most cited

Restraint of Powassan virus replication by TRIM5α facilitates viral avoidance of antiviral immunity

Rebecca M. Broeckel, Emily A. Fitzmeyer, Eva Chebishev, Jeffrey G. Shannon, Byron Shue, Adam Hage, Stephanie J. Spada, Efrosini Artikis, Abhilash I. Chiramel, Kristin L. McNally, Charles L. Larson, Maarit von Kutzleben, Shelly J. Robertson, Danielle K. Offerdahl, Hilary Ann Lakin, , Sonja M. Best

The paper investigates how TRIM5α restricts orthoflavivirus replication and identifies a mutation in POWV's NS3 gene that allows it to evade TRIM5α inhibition.

Communications Biology · Jul 7, 2026Peer-reviewedMicrobiology

Human ESCRT-I and ALIX function as scaffolding helical filaments in vivo

Stephanie J. Spada, Kevin M. Rose, Paola Sette, Sarah K. O’Connor, Vincent Dussupt, V. Siddartha Yerramilli, Kunio Nagashima, Virginie Helle Sjoelund, Phillip Cruz, Juraj Kabát, Sundar Ganesan, Margery G. Smelkinson, Aleksandra Nita‐Lazar, Forrest H. Hoyt, Suzanne Scarlata, , Fadila Bouamr

This study shows ESCRT-I and ALIX form helical filaments in vivo, serving as structural scaffolds and ESCRT-III assembly templates for membrane scission and viral budding.

bioRxiv · May 1, 2024 · PreprintCell Biology