Author

Ana Sofia Alberto‐Silva

Medical University of ViennaORCID 0000-0001-5662-0581Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Elena BossiiD· 2 shared Harald H. SitteiD· 2 shared Manan BhattiD· 2 shared Thomas StockneriD· 2 shared Andre BazzoneiD· 1 shared Erika LazzariniD· 1 shared Guido DomingoiD· 1 shared Hailey A. BockiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersPharmacology & Toxicology

Elena BossiORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologyJournal of NeurochemistryPeer-reviewedJun 19, 2024

Bioisosteric analogs of MDMA with improved pharmacological profile

Ana Sofia Alberto‐Silva, Selina Hemmer, Hailey A. Bock…·Harald H. Sitte

This study evaluates three MDMA bioisosteres for improved pharmacological profiles, finding reduced off-target receptor activity and altered hepatic metabolism compared to MDMA.

13 citations

humanexperimental assay

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NeuroscienceCellular and Molecular Life SciencesPeer-reviewedJun 17, 2024

Unveiling the crucial role of betaine: Modulation of GABA homeostasis via SLC6A1 transporter (GAT1)

Manan Bhatt, Erika Lazzarin, Ana Sofia Alberto‐Silva…·Elena Bossi

This study identifies betaine as a slow substrate of GAT1, showing it modulates GABA reuptake and helps maintain GABA homeostasis, protecting neurons from excitotoxicity.

15 citations

experimental assay

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