Author

Erika Lazzarin

Medical University of ViennaORCID 0000-0001-6520-2664Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Harald H. SitteiD· 2 shared Ralph GradischiD· 2 shared Thomas StockneriD· 2 shared Ana Sofia Alberto‐SilvaiD· 1 shared Andre BazzoneiD· 1 shared Baruch I. Kanner· 1 shared Chiara Sebastianelli-SchoditschiD· 1 shared Dániel SzöllősiiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Harald H. SitteORCID

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2 papers

Recent·Most cited

NeuroscienceCellular and Molecular Life SciencesPeer-reviewedJun 17, 2024

Unveiling the crucial role of betaine: Modulation of GABA homeostasis via SLC6A1 transporter (GAT1)

Manan Bhatt, Erika Lazzarin, Ana Sofia Alberto‐Silva…·Elena Bossi

This study identifies betaine as a slow substrate of GAT1, showing it modulates GABA reuptake and helps maintain GABA homeostasis, protecting neurons from excitotoxicity.

15 citations

experimental assay

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Molecular BiologybioRxivPreprintOct 10, 2023

Interaction of GAT1 with sodium ions: from efficient recruitment to stabilisation of substrate and conformation

Erika Lazzarin, Ralph Gradisch, Sophie M.C. Skopec…·Thomas Stockner

This study identifies a novel sodium recruiting site in GAT1 and shows how sodium binding stabilizes the transporter's conformation and enhances GABA uptake.

1 citation

humanstatistical model

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