Bernadette Carroll

This study identifies ROS-dependent Akt-mTORC1 dysregulation in senescent myoblasts and shows antioxidants can suppress inflammation and promote differentiation but also induce cell death.

This study identifies TMEM263 as an ER-resident protein essential for lipid droplet formation and growth, showing its role in lipid condensation and organismal development.

This study shows that senescent cells survive by enhancing lysosomal quality control and repair mechanisms, which can be targeted to induce cell death.