Sussan Nourshargh

This study identifies GPR84 as a regulator of immune cell extravasation by enabling uropod de-adhesion during inflammation, showing its role in terminating leukocyte migration.

This study presents a single-cell epigenomic and transcriptomic atlas of aged mice under germ-free conditions, revealing sterile inflammation as an intrinsic ageing feature.

This paper shows that Piezo1 mechanosensing triggers endothelial Weibel-Palade body exocytosis, linking mechanical forces to inflammation and haemostasis through VWF release and leukocyte capture.

The paper shows that neutrophils use endothelial membrane tunnels for paracellular extravasation, formed by membrane lifting and indentation without requiring PECAM-1 or VE-cadherin.