Author

Nicholas A. Marinelli

University of South CarolinaORCID 0000-0001-5689-1250Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Sofia B. LizarragaiD· 2 shared Abbie M. Maguire· 1 shared Brian Yoon· 1 shared Calvin S. LeungiD· 1 shared Collin Cheatle· 1 shared Ece Dilber Gamsiz UzuniD· 1 shared Emma H. NealiD· 1 shared Ethan S. LippmanniD· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersNeuroscience

Sofia B. LizarragaORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeuroscienceHuman Molecular GeneticsPeer-reviewedJan 9, 2023

Dysregulation of The Chromatin Environment Leads to Differential Alternative Splicing as A Mechanism Of Disease In a Human Model of Autism Spectrum Disorders

Calvin S. Leung, Shoshana J. Rosenzweig, Brian Yoon…·Sofia B. Lizarraga

This study shows that VPA exposure alters chromatin environment, leading to changes in alternative splicing and gene expression in human cortical neurons, which may contribute to ASD pathogenesis.

15 citations

humanbulk RNA-seq

𝕏 PostBluesky

NeuroscienceJournal of NeurochemistryPeer-reviewedOct 30, 2021

Influence of basal media composition on barrier fidelity within human pluripotent stem cell-derived blood-brain barrier models

Emma H. Neal, Ketaki A. Katdare, Yajuan Shi…·Ethan S. Lippmann

This study shows that different basal media compositions significantly affect BBB properties in human iPSC-derived BMEC-like cells, influencing passive and active transport and signaling pathways.

17 citations

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintSep 27, 2021

Overcoming the effect of ASH1L haploinsufficiency on stem cells amenability to genome editing and differentiation into the neuronal lineage - a technical report

Seon Hye Cheon, Foster D. Ritchie, Janay M. Vacharasin…·Sofia B. Lizarraga

This paper describes protocols to overcome ASH1L haploinsufficiency in stem cells, improving genome editing and neuronal differentiation efficiency.

1 citation

humanCRISPR screen

𝕏 PostBluesky