Author

Seon Hye Cheon

University of South Carolina

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Foster D. RitchieiD· 2 shared Mikayla M. McCordiD· 2 shared Sofia B. LizarragaiD· 2 shared Allison M. Culver· 1 shared Anna M. BagnelliD· 1 shared Austin J. Smith· 1 shared Beata Henry· 1 shared Carin M. PapendorpiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Foster D. RitchieORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Patient brain organoids identify a link between the 16p11.2 copy number variant and the RBFOX1 gene.

Milos Kostic, Joseph J. Raymond, Christophe A. C. Freyre, Beata Henry, Tayfun Tumkaya, Jivan Khlghatyan, Jill Dvornik, Jingyao Li, Jack S. Hsiao, Seon Hye Cheon, Jonathan Chung, Yishan Sun, Ricardo E. Dolmetsch, Kathleen A. Worringer, Robert J. Ihry

The paper uses patient brain organoids to show that 16p11.2 CNVs affect RBFOX1 expression and link it to neurodevelopmental disorders.

ACS Chemical Neuroscience · Oct 30, 2023Peer-reviewedNeuroscience

Overcoming the effect of ASH1L haploinsufficiency on stem cells amenability to genome editing and differentiation into the neuronal lineage - a technical report

Seon Hye Cheon, Foster D. Ritchie, Janay M. Vacharasin, Nicholas A. Marinelli, Collin Cheatle, Mikayla M. McCord, Kaitlin Cox, Sofia B. Lizarraga

This paper describes protocols to overcome ASH1L haploinsufficiency in stem cells, improving genome editing and neuronal differentiation efficiency.

bioRxiv · Sep 27, 2021 · PreprintNeuroscience

ASH1L REGULATES THE STRUCTURAL DEVELOPMENT OF NEURONAL CIRCUITRY BY MODULATING BDNF/TrkB SIGNALING IN HUMAN NEURONS

Seon Hye Cheon, Allison M. Culver, Anna M. Bagnell, Foster D. Ritchie, Janay M. Clytus, Mikayla M. McCord, Carin M. Papendorp, Evelyn Chukwurah, Austin J. Smith, Mara H. Cowen, Pankaj S. Ghate, Shannon William Davis, Judy Shih-Hwa Liu, Sofia B. Lizarraga

This study shows ASH1L regulates neuronal connectivity by modulating BDNF/TrkB signaling through its interaction with PRC2 in human neurons, linking ASH1L mutations to autism pathogenesis.

bioRxiv · Feb 18, 2020 · PreprintNeuroscience