Author

Rebeca T. King

Columbia UniversityORCID 0000-0001-5712-4539Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alejandro ChaveziD· 1 shared Bhavini Rana· 1 shared Carl A. MitchelliD· 1 shared Diego MaríniD· 1 shared Dieter M. EgliiD· 1 shared Everett WeinsteiniD· 1 shared George D. LampeiD· 1 shared Jia L. XuiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetics

Alejandro ChavezORCID

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2 papers

Recent·Most cited

GeneticsNature BiotechnologyPeer-reviewedMar 29, 2023

Targeted DNA integration in human cells without double-strand breaks using CRISPR RNA-guided transposases

George D. Lampe, Rebeca T. King, Tyler S. Halpin-Healy…·Samuel H. Sternberg

This paper develops a CRISPR-guided transposon system for DSB-free DNA integration in human cells, improving efficiency and reducing off-target effects.

146 citationstop 1%

humanCRISPR screen

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GeneticsCellPeer-reviewedOct 29, 2020

Reading frame restoration at the EYS locus, and allele-specific chromosome removal after Cas9 cleavage in human embryos

Michael V. Zuccaro, Jia L. Xu, Carl A. Mitchell…·Dieter M. Egli

The paper evaluates Cas9-induced repair outcomes at the EYS locus in human embryos, showing microhomology-mediated end joining restores reading frames without mosaicism, while unrepaired breaks lead to chromosome loss.

303 citationstop 1%

humanexperimental assay

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