Author

Emily E. Lewis

University of PennsylvaniaORCID 0000-0001-5721-0787Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Organism:rat· 2 Research Focus:cell type annotation· 1 Organism:non-human primate· 1

Frequent Co-Authors

Andrew Jesse ConnelliD· 3 shared Barton F. HaynesiD· 3 shared Beatrice H. HahniD· 3 shared Daniel W. KulpiD· 3 shared George M. ShawiD· 3 shared John W. CareyiD· 3 shared Juliette M. RandoiD· 3 shared Kirsten J. SowersiD· 3 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Andrew Jesse ConnellORCID

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3 papers

Recent·Most cited

ImmunologyThe Journal of Experimental MedicinePeer-reviewedJul 10, 2025

HIV-1 neutralizing antibodies in SHIV-infected macaques recapitulate structurally divergent modes of human V2 apex recognition with a single D gene

Ryan S. Roark, Rumi Habib, Jason Gorman…·Lawrence S. Shapiro

This study isolates and characterizes V2 apex-directed neutralizing antibodies from SHIV-infected macaques, revealing structural and genetic features that enable broad neutralization.

21 citationstop 2%

ratproteomics

𝕏 PostBluesky

MicrobiologyCell ReportsPeer-reviewedJun 1, 2025

Transient glycan-shield reduction induces CD4-binding site broadly neutralizing antibodies in SHIV-infected macaques

Daniel J. Morris, Jason Gorman, Tongqing Zhou…·George M. Shaw

This study shows that transient glycan deletions in SHIVs can induce CD4-binding site broadly neutralizing antibodies in macaques, offering a model for HIV vaccine design.

8 citations

non-human primateproteomics

𝕏 PostBluesky

ImmunologybioRxivPreprintMay 3, 2025

Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV-1 V2 apex broadly neutralizing antibody development

Rumi Habib, Ryan S. Roark, Hui Li…·George M. Shaw

The paper identifies B cell priming as the main obstacle to developing HIV-1 V2 apex broadly neutralizing antibodies in SHIV-infected macaques.

8 citations

ratproteomics

𝕏 PostBluesky