Author

Jason Gorman

National Institutes of HealthORCID 0000-0002-3775-6560Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:non-human primate· 1 Organism:rat· 1

Frequent Co-Authors

Ajay SinghiD· 2 shared Andrew Jesse ConnelliD· 2 shared Barton F. HaynesiD· 2 shared Beatrice H. HahniD· 2 shared Daniel W. KulpiD· 2 shared Emily E. LewisiD· 2 shared George M. ShawiD· 2 shared John W. CareyiD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Ajay SinghORCID

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2 papers

Recent·Most cited

HIV-1 neutralizing antibodies in SHIV-infected macaques recapitulate structurally divergent modes of human V2 apex recognition with a single D gene

Ryan S. Roark, Rumi Habib, Jason Gorman, Hui Joyce Li, Andrew Jesse Connell, Mattia Bonsignori, Yicheng Guo, Michael P. Hogarty, Adam S. Olia, Kirsten J. Sowers, Baoshan Zhang, Frédéric Bibollet‐Ruche, Tatsiana Bylund, Sean Callaghan, John W. Carey, , Lawrence S. Shapiro

This study isolates and characterizes V2 apex-directed neutralizing antibodies from SHIV-infected macaques, revealing structural and genetic features that enable broad neutralization.

The Journal of Experimental Medicine · Jul 10, 2025Peer-reviewedImmunology

Transient glycan-shield reduction induces CD4-binding site broadly neutralizing antibodies in SHIV-infected macaques

Daniel J. Morris, Jason Gorman, Tongqing Zhou, Jinery Lora, Andrew J. Connell, Hui Li, Weimin Liu, Ryan S. Roark, Mary S. Campion, John W. Carey, Rumi Habib, Yingying Li, Christian L. Martella, Younghoon Park, Ajay Singh, , George M. Shaw

This study shows that transient glycan deletions in SHIVs can induce CD4-binding site broadly neutralizing antibodies in macaques, offering a model for HIV vaccine design.

Cell Reports · Jun 1, 2025Peer-reviewedMicrobiology