Carlos Portera‐Cailliau

This study shows that parvalbumin interneurons drive cortical network desynchronization and increased population activity dimensionality during development.

The paper identifies positive and negative prediction error neurons in mouse somatosensory cortex during an oddball paradigm, showing how they encode stimulus features and statistical context in a hierarchical predictive processing framework.

The paper investigates neural responses to social and non-social touch in mice, finding that autism model mice (Fmr1 KO) fail to distinguish social from non-social touch at the circuit level, potentially contributing to social avoidance.

The paper shows that FXS mice show impaired performance on distractor tasks, linked to reduced modulation of VIP interneurons.

The paper introduces a head-fixed social touch assay in mice to study aversive responses in autism models, finding increased avoidance and aversive facial expressions in ASD models compared to controls.

This study investigates whether stroke-induced cortical plasticity involves remapping to new circuits or potentiating existing ones, finding no remapping but increased response reliability in pre-existing circuits.

EZcalcium provides an open-source, GUI-based tool for analyzing calcium imaging data, integrating motion correction, segmentation, signal extraction, and deconvolution.

This study identifies parvalbumin neuron dysfunction in V1 as a mediator of impaired perceptual learning in Fragile X syndrome and shows that restoring PV neuron activity can reverse the deficit.

The paper tests the E/I imbalance model in Fragile X syndrome using computational modeling and 2-photon imaging data, finding it insufficient and revealing stage-dependent circuit changes.