Ernest V. Pedapati

The paper analyzes EEG data from 4,812 individuals to identify shared and distinct neurophysiological signatures across psychiatric conditions and rare genetic variants.

This study finds reduced neural entrainment to word-level speech patterns in children with Fragile X Syndrome, indicating impaired statistical learning.

This study analyzes alpha oscillations in Fragile X syndrome, revealing sex-specific and region-specific abnormalities in burst characteristics that correlate with clinical symptoms.

The paper introduces ERSSP, an EEG analysis framework to study extralemniscal thalamocortical activity, validated in Fragile X Syndrome showing increased spatial power increases.

This study investigates neural correlates of auditory hypersensitivity in FXS using EEG source analysis, finding frontal cortex hyperactivation and gamma desynchrony linked to auditory processing issues.

This study uses iPSC-derived neurons to show that FMRP deficiency in fragile X syndrome leads to m6A-mediated transcriptome dysregulation, causing synaptic dysfunction and suggesting therapeutic targets.

This paper reviews US professional society guidelines for genetic testing in neurodevelopmental disorders and highlights the need for unified, updated, and accessible cross-specialty guidelines.

The paper shows that FXS mice show impaired performance on distractor tasks, linked to reduced modulation of VIP interneurons.

This study identifies parvalbumin neuron dysfunction in V1 as a mediator of impaired perceptual learning in Fragile X syndrome and shows that restoring PV neuron activity can reverse the deficit.