Michael Andreas Welte

This study shows that HSF maintains basal HSP83/HSP90 expression to support developmental growth in Drosophila, with loss of HSF causing developmental defects and reduced chaperone levels.

The paper investigates fatty acid trafficking during Drosophila oogenesis and shows that lipid droplets buffer mitochondrial lipotoxicity by storing and mobilizing fatty acids for energy production.

This study shows that H2A.Z levels act as a timer for the maternal-zygotic transition in Drosophila and zebrafish, influencing developmental timing through both nuclear and non-nuclear mechanisms.

The paper identifies Jabba as a downstream effector of prostaglandin signaling that promotes actin remodeling during Drosophila oogenesis, revealing two distinct PG-dependent pathways for actin remodeling.

The paper shows Drosophila embryos spatially sort nutrients into distinct tissues during gastrulation, and mutants disrupt this sorting, delaying nutrient turnover.