Michelle S. Giedt

This study shows that ATGL-mediated lipid droplet lipolysis is essential for collective migration in Drosophila border cells by regulating energy production and mitochondrial function.

This study shows that prostaglandin signaling regulates nucleoskeletal remodeling during Drosophila border cell migration, which facilitates collective migration.

The paper identifies Jabba as a downstream effector of prostaglandin signaling that promotes actin remodeling during Drosophila oogenesis, revealing two distinct PG-dependent pathways for actin remodeling.

This study shows that PLIN2 regulates lipophagy in beta cells to prevent fatty acid accumulation in mitochondria, which impairs insulin secretion and mitochondrial function.